ArchDaily ShareFacebookTwitterPinterestWhatsappMailOrhttps://www.archdaily.com/405358/20-social-housing-in-paris-h20-architects Clipboard ShareFacebookTwitterPinterestWhatsappMailOrhttps://www.archdaily.com/405358/20-social-housing-in-paris-h20-architects Clipboard Photographs: Stéphane Chalmeau+ 24 Share 2013 Architects: h2o architectes Area Area of this architecture project Area: 1850 m² Area: 1850 m² Year Completion year of this architecture project France 2013 “COPY” Year: 20 Social Housing in Paris / h2o architectesSave this projectSave20 Social Housing in Paris / h2o architectesSave this picture!© Stéphane ChalmeauApartments•Paris, France Projects 20 Social Housing in Paris / h2o architectes CopySave this picture!© Stéphane ChalmeauRecommended ProductsWoodParklex International S.L.Wood cladding – FacadeWoodEGGERLaminatesWoodLunawoodThermowood FacadesWoodAccoyaAccoya® Cladding, Siding & FacadesText description provided by the architects. The project of the rue Godefroy Cavaignac in Paris consisted in the rehabilitation of a building which did not meet hygiene and security standards into new social housing. The agency’s aim was to renew the image of the building in the street while responding to the requirements of the «patrimoine habitat environnement» certification. The project is largely based on the building extension, contemporary reinvention of the bow-window, inserted in the prolongation of the unfinished 19th century façade. Save this picture!© Stéphane ChalmeauThe alternation of voids and solids as well as the diagonal cutting of the volumes break the visual monotony of the alignment of the buildings in the street and offer new and interesting views onto the rue de Charonne. Save this picture!© Stéphane ChalmeauInside, the apartments benefit from new space and comfort including, for some of them, a small space for gardening, a loggia or balcony. Save this picture!© Stéphane ChalmeauThe courtyard is transformed into a planted patio which is made visible thanks to a transparent wall from the street. A page is turned, social life is reinvented. Save this picture!Floor PlanProject gallerySee allShow lessCity Works: Provocations for Chicago’s Urban FutureEventRebollar Complex / SANTOSCREATIVOS + E85Selected ProjectsProject locationAddress:Rue Godefroy Cavaignac, 75011 Paris, FranceLocation to be used only as a reference. It could indicate city/country but not exact address. Share Photographs Apartments “COPY” Year: CopyAbout this officeh2o architectesOfficeFollowProductConcrete#TagsProjectsBuilt ProjectsSelected ProjectsResidential ArchitectureHousingApartmentsParisHousingResidentialFrancePublished on July 25, 2013Cite: “20 Social Housing in Paris / h2o architectes” 25 Jul 2013. ArchDaily. Accessed 11 Jun 2021.
Full Name* Message* Share on FacebookShare on TwitterShare on LinkedinShare via Email Share via Shortlink (iStock/Photo Illustration by Kevin Rebong for The Real Deal)The value of America’s luxury malls is roughly half what it was in 2016, a worrying sign for an industry that has long considered such malls to be safer than lower-tier alternatives.A-rated malls, which generate an average of $750 in sales per square foot, made a strong comeback after the last financial crisis, according to CNBC. But a new report from Green Street estimates that the value of such malls has fallen about 45 percent since 2016 levels.Read moreMall owner keeps growing as some of its properties deteriorateSeven big mall owners in precarious stateSimon completes acquisition of high-end mall owner Taubman Email Address* Share via Shortlink One reason for the decline is the flagging fortunes of department stores, which traditionally brought a lot of customers into malls. More recently, the pandemic led to temporary closures and a shift away from in-person shopping.“A mall is a fragile ecosystem,” Green Street said. “When conditions deteriorate markedly, a mall can enter a ‘death spiral’ — where the lower sales productivity leads to falling occupancy, which results in fewer visitors attracted to a diminishing group of retailers, which continues the cycle of decreasing sales and occupancy.”“This vicious cycle can continue until the mall becomes obsolete.”CNBC noted that shares in the country’s biggest mall owner, Simon Property Group, fell 32 percent last year. The company owns a large number of the country’s roughly 1,000 Class A malls.However, Green Street reserved its biggest concerns for B- and C-rated malls, which it predicted will need to be repurposed in the next few years.[CNBC] — Sylvia Varnham O’ReganContact Sylvia Varnham O’Regan TagsmallsRetailsimon property group
Today, Outside Lands, the nationally renowned festival that takes place in San Francisco’s Golden Gate Park, has announced its 2018 lineup. At the top of the bill are The Weeknd, Florence & The Machine, Janet Jackson, Future, Beck, Odesza, Bon Iver, and DJ Snake. Outside Lands will also host performances by Portugal. The Man, N.E.R.D., CHVRCHES, James Blake, Jamie xx, Huey Lewis & The News, Mac DeMarco, Chromeo, Tycho, Big Gigantic, Father John Misty, Tash Sultana, Chicano Batman, The Internet, and dozens of other nationally touring acts.Outside Lands will take over Golden Gate Park in San Francisco, California, from August 10th through 12th this summer. General admission and VIP passes go on sale on Thursday, April 5th, at 10 a.m. (PST). For more information about the festival or to snag tickets when they go on sale, head over to the festival’s website here.
In this video, Wyss Director Donald Ingber and technology development fellow Kambez Benam explain how the integrated smoking device mimics normal cigarette smoke exposure and how it can impact research into the causes of COPD and into new biomarkers and therapeutics. Credit: Wyss Institute at Harvard University Progress in figuring out how exactly cigarette smoke worsens COPD, a so-far irreversible inflammatory disease of the small airways of the lung, has been glacial because researchers lack faithful models. Classical culture systems with human small airway cells are unable to reproduce the breathing motions of the lung and commonly used laboratory animals cannot reflect human smoking because they breathe through their noses, and their inflammatory responses differ from those in humans. In addition, human clinical studies have revealed great variability in the physiological and biochemical responses between patients, and they usually do not allow direct comparisons of smoke exposure versus no exposure in the same individual.The device leverages the Wyss Institute team’s previously developed human lung small airway-on-a-chip model for inflammatory disorders.“The device enables us for the first time to compare responses of human small airway tissues, from both normal individuals and COPD patients, before and after they are exposed to cigarette smoke delivered through physiological breathing outside the human body. We can now begin to decipher which cell types, cellular functions, and genes contribute to smoke-induced injury in normal lung, as well as during COPD exacerbations in individual patients, and thereby, identify common as well as patient-specific disease factors,” said Wyss Director Donald Ingber, the Judah Folkman Professor of Vascular Biology at Harvard Medical School and Boston Children’s Hospital and professor of bioengineering at the Harvard John A. Paulson School of Engineering and Applied Sciences.In the microfluidic small airway-on-a-chip, one hollow microchannel is lined by living human bronchiolar epithelium, obtained from COPD patients or healthy people, which is exposed to air delivered under normal breathing motions by the smoking instrument. Cell culture medium is continually flowed through a parallel running channel separated from the first by a porous membrane to support the epithelium for up to four weeks, and to create a so-called air-liquid interface similar to that present in actual lung airway.The cigarettes are lit and burned in the rotating unit of the smoking machine in intervals that mimic breathing patterns and smoking of real smokers. Credit: Wyss Institute at Harvard University“In order to translate observed breathing patterns and smoking behavior into biological effects, we combined the small airway-on-a-chip with a smoking machine that burns cigarettes and a microrespirator that inhales and exhales small volumes of cigarette smoke and fresh air in and out of the epithelium-lined channel in programmable intervals mimicking true smoking behavior,” said Richard Novak, a co-author of the study and a senior staff engineer at the Wyss Institute, who helped design the smoking instrument.The integrated smoking system recapitulates the complex oxidant-induced biological responses of normal lung cells to toxic molecules present in cigarette smoke as well as COPD-specific inflammatory responses. “We identified a COPD-specific signature by comparing gene expression changes in COPD-derived chips exposed or not exposed to smoke and subtracting the changes that we see in chips made from healthy lung chips. This type of analysis could lead to future biomarkers, drug targets, and possibly more personalized approaches to COPD in the future,” said first author Kambez H. Benam, a Wyss Institute technology development fellow. The team demonstrated that they can use this approach to investigate potential toxicity profiles of emerging tobacco-related products such as e-cigarettes.Benam was also able to analyze the behavior of mucus-transporting cilia protruding from the small airway cells into the smoke-exposed microfluidic channel in an automated high-throughput fashion working with Janna Nawroth, a past Wyss technology development fellow with co-author Kit Parker, a Wyss core faculty member and the Tarr Family Professor of Bioengineering and Applied Physics at the Harvard School of Engineering and Applied Sciences.“We found that cilia beating becomes more heterogeneous and reaches lower frequencies in chips exposed to whole cigarette smoke,” said Benam, who recently also received a Baxter Young Investigator award for his work at the Wyss Institute.“The power of the technology is that it allows us to directly analyze the effect of a stimulus, in this case smoke exposure, on lung in what might be thought of as an in vitro human ‘pre-clinical’ study,” Ingber said. “This is hard to do in a standard human clinical study where one compares patients with a history of smoking versus those who do not smoke because all of the patients have different histories, backgrounds, and patterns of exposure to the stimulus.”The study was also authored by Mariko Hirano-Kobayashi, a past research fellow with Ingber at the Wyss Institute and Boston Children’s Hospital, Wyss research assistants Youngjae Choe and Thomas Ferrante, present and former Wyss senior staff scientists Rachelle Prantil-Braun and Anthony Bahinski, and James C. Weaver, a Wyss Institute research scientist.The project was funded by the Defense Advanced Research Project Agency and the Wyss Institute for Biologically Inspired Engineering at Harvard University.SaveSaveSaveSaveSaveSave While it is well known that cigarette smoking is a major cause of lung disease, and a key exacerbating factor for patients suffering from chronic obstructive pulmonary disease (COPD), it has not been possible to effectively model its deleterious effects on human lungs under normal breathing conditions.In an article in Cell Systems, a multidisciplinary team at the Wyss Institute for Biologically Inspired Engineering at Harvard University describes an instrument they engineered that can “breathe” in and out, actively smoke regular and electronic cigarettes much like a human, and deliver the smoke to microfluidic organs-on-chips lined by human lung small airway cells isolated from non-smokers or COPD patients. The integrated smoking system gives researchers a better understanding of smoke-related pathological changes in individual smokers, and could facilitate the discovery of more accurate biomarkers and new therapeutic targets.Smoking Human Lung Small Airway on a Chip <a href=”https://www.youtube.com/watch?v=VewOqUnwXG0″ rel=”nofollow” target=”_blank”> <img src=”https://img.youtube.com/vi/VewOqUnwXG0/0.jpg” alt=”0″ title=”How To Choose The Correct Channel Type For Your Video Content ” /> </a>
BROOKVILLE, Ind. — On Halloween, the Franklin County High School FCCLA girls went Trick or Treating for a good cause.The Family, Careers and Community Leaders of America collected can goods from nearby area homes, and donated them to the Southeastern Indiana Economic Opportunity Corporation.The girls were able to collect several hundred can goods in grocery bags.